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G3-C12 TFA (848301-94-0 free base)

CAS No.

G3-C12 TFA (848301-94-0 free base) ( )

Catalog No. M29993 CAS No.

G3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    G3-C12 TFA (848301-94-0 free base)
  • Note
    Research use only, not for human use.
  • Brief Description
    G3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.
  • Description
    G3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.(In Vitro):G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 (TFA) bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.
  • Synonyms
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Kd: 88 nM (Galectin-3)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    1873
  • Molecular Formula
    C74H115N23O23S2.C2HF3O2
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : ≥ 50 mg/mL (26.70 mM)
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19(10):933-43.
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